1,446 research outputs found
Smell you later - the repelling effect of secondary plant compounds against water voles and common voles
Fischer, D., Prokop, A., Wink, M., Mattes, H., Jacob, J
Neutron-induced background in the CONUS experiment
CONUS is a novel experiment aiming at detecting elastic neutrino nucleus
scattering in the fully coherent regime using high-purity Germanium (Ge)
detectors and a reactor as antineutrino () source. The detector setup
is installed at the commercial nuclear power plant in Brokdorf, Germany, at a
very small distance to the reactor core in order to guarantee a high flux of
more than 10/(scm). For the experiment, a good
understanding of neutron-induced background events is required, as the neutron
recoil signals can mimic the predicted neutrino interactions. Especially
neutron-induced events correlated with the thermal power generation are
troublesome for CONUS. On-site measurements revealed the presence of a thermal
power correlated, highly thermalized neutron field with a fluence rate of
(74530)cmd. These neutrons that are produced by nuclear
fission inside the reactor core, are reduced by a factor of 10 on
their way to the CONUS shield. With a high-purity Ge detector without shield
the -ray background was examined including highly thermal power
correlated N decay products as well as -lines from neutron
capture. Using the measured neutron spectrum as input, it was shown, with the
help of Monte Carlo simulations, that the thermal power correlated field is
successfully mitigated by the installed CONUS shield. The reactor-induced
background contribution in the region of interest is exceeded by the expected
signal by at least one order of magnitude assuming a realistic ionization
quenching factor of 0.2.Comment: 28 pages, 28 figure
Pearling: stroke segmentation with crusted pearl strings
We introduce a novel segmentation technique, called Pearling, for the semi-automatic extraction of idealized models of networks of strokes (variable width curves) in images. These networks may for example represent roads in an aerial photograph, vessels in a medical scan, or strokes in a drawing. The operator seeds the process by selecting representative areas of good (stroke interior) and bad colors. Then, the operator may either provide a rough trace through a particular path in the stroke graph or simply pick a starting point (seed) on a stroke and a direction of growth. Pearling computes in realtime the centerlines of the strokes, the bifurcations, and the thickness function along each stroke, hence producing a purified medial axis transform of a desired portion of the stroke graph. No prior segmentation or thresholding is required. Simple gestures may be used to trim or extend the selection or to add branches. The realtime performance and reliability of Pearling results from a novel disk-sampling approach, which traces the strokes by optimizing the positions and radii of a discrete series of disks (pearls) along the stroke. A continuous model is defined through subdivision. By design, the idealized pearl string model is slightly wider than necessary to ensure that it contains the stroke boundary. A narrower core model that fits inside the stroke is computed simultaneously. The difference between the pearl string and its core contains the boundary of the stroke and may be used to capture, compress, visualize, or analyze the raw image data along the stroke boundary
Full-Polarization Observations of OH Masers in Massive Star-Forming Regions: I. Data
We present full-polarization VLBA maps of the ground-state, main-line, 2 Pi
3/2, J = 3/2 OH masers in 18 Galactic massive star-forming regions. This is the
first large polarization survey of interstellar hydroxyl masers at VLBI
resolution. A total of 184 Zeeman pairs are identified, and the corresponding
magnetic field strengths are indicated. We also present spectra of the NH3
emission or absorption in these star-forming regions. Analysis of these data
will be presented in a companion paper.Comment: 111 pages, including 42 figures and 21 tables, to appear in ApJ
HNO Protects the Myocardium against Reperfusion Injury, Inhibiting the mPTP Opening via PKCε Activation
Donors of nitroxyl (HNO), the one electron-reduction product of nitric oxide (NO. ), posi-tively modulate cardiac contractility/relaxation while limiting ischemia-reperfusion (I/R) injury. The mechanisms underpinning HNO anti-ischemic effects remain poorly understood. Using isolated perfused rat hearts subjected to 30 min global ischemia/1 or 2 h reperfusion, here we tested whether, in analogy to NO., HNO protection requires PKCε translocation to mitochondria and KATP channels activation. To this end, we compared the benefits afforded by ischemic preconditioning (IPC; 3 cycles of I/R) with those eventually granted by the NO. donor, diethylamine/NO, DEA/NO, and two chemically unrelated HNO donors: Angeli’s salt (AS, a prototypic donor) and isopropyla-mine/NO (IPA/NO, a new HNO releaser). All donors were given for 19 min before I/R injury. In control I/R hearts (1 h reperfusion), infarct size (IS) measured via tetrazolium salt staining was 66 ± 5.5% of the area at risk. Both AS and IPA/NO were as effective as IPC in reducing IS [30.7 ± 2.2 (AS), 31 ± 2.9 (IPA/NO), and 31 ± 0.8 (IPC), respectively)], whereas DEA/NO was significantly less so (36.2 ± 2.6%, p < 0.001 vs. AS, IPA/NO, or IPC). IPA/NO protection was still present after 120 min of reperfusion, and the co-infusion with the PKCε inhibitor (PKCV1-2500 nM) prevented it (IS = 30 ± 0.5 vs. 61 ± 1.8% with IPA/NO alone, p < 0.01). Irrespective of the donor, HNO anti-ischemic effects were insensitive to the KATP channel inhibitor, 5-OH decanoate (5HD, 100 μM), that, in contrast, abrogated DEA/NO protection. Finally, both HNO donors markedly enhanced the mitochondrial permeability transition pore (mPTP) ROS threshold over control levels (≅35–40%), an action again insensitive to 5HD. Our study shows that HNO donors inhibit mPTP opening, thus limiting myo-cyte loss at reperfusion, a beneficial effect that requires PKCε translocation to the mitochondria but not mitochondrial K+ channels activation
Radio Continuum and Recombination Line Study of UC HII Regions with Extended Envelopes
We have carried out 21 cm radio continuum observations of 16 UC HII regions
using the VLA (D-array) in search of associated extended emission. We have also
observed H76 recombination line towards all the sources and
He76 line at the positions with strong H76 line emission. The
UC HII regions have simple morphologies and large (>10) ratios of single-dish
to VLA fluxes. Extended emission was detected towards all the sources. The
extended emission consists of one to several compact components and a diffuse
extended envelope. All the UC HII regions but two are located in the compact
components, where the UC HII regions always correspond to their peaks. The
compact components with UC HII regions are usually smaller and denser than
those without UC HII regions. Our recombination line observations indicate that
the ultracompact, compact, and extended components are physically associated.
The UC HII regions and their associated compact components are likely to be
ionized by the same sources on the basis of the morphological relations
mentioned above. This suggests that almost all of the observed UC HII regions
are not `real' UC HII regions and that their actual ages are much greater than
their dynamical age (<10000 yr). We find that most of simple UC HII regions
previously known have large ratios of single-dish to VLA fluxes, similar to our
sources. Therefore, the `age problem' of UC HII regions does not seem to be as
serious as earlier studies argued. We present a simple model that explains
extended emission around UC HII regions. Some individual sources are discussed.Comment: 29 pages, 28 postscript figures, Accepted for publication in Ap
A massive cluster of Red Supergiants at the base of the Scutum-Crux arm
We report on the unprecedented Red Supergiant (RSG) population of a massive
young cluster, located at the base of the Scutum-Crux Galactic arm. We identify
candidate cluster RSGs based on {\it 2MASS} photometry and medium resolution
spectroscopy. With follow-up high-resolution spectroscopy, we use CO-bandhead
equivalent width and high-precision radial velocity measurements to identify a
core grouping of 26 physically-associated RSGs -- the largest such cluster
known to-date. Using the stars' velocity dispersion, and their inferred
luminosities in conjuction with evolutionary models, we argue that the cluster
has an initial mass of 40,000\msun, and is therefore among the most
massive in the galaxy. Further, the cluster is only a few hundred parsecs away
from the cluster of 14 RSGs recently reported by Figer et al (2006). These two
RSG clusters represent 20% of all known RSGs in the Galaxy, and now offer the
unique opportunity to study the pre-supernova evolution of massive stars, and
the Blue- to Red-Supergiant ratio at uniform metallicity. We use GLIMPSE,
MIPSGAL and MAGPIS survey data to identify several objects in the field of the
larger cluster which seem to be indicative of recent region-wide starburst
activity at the point where the Scutum-Crux arm intercepts the Galactic bulge.
Future abundance studies of these clusters will therefore permit the study of
the chemical evolution and metallicity gradient of the Galaxy in the region
where the disk meets the bulge.Comment: 49 pages, 22 figures. Accepted for publication in ApJ. Version with
hi-res figures can be found at http://www.cis.rit.edu/~bxdpci/RSGC2.pd
Microbiome dynamics during the HI-SEAS IV mission, and implications for future crewed missions beyond Earth.
Background: Human health is closely interconnected with its microbiome. Resilient microbiomes in, on, and around the human body will be key for safe and successful long-term space travel. However, longitudinal dynamics of microbiomes inside confined built environments are still poorly understood. Herein, we used the Hawaii Space Exploration Analog and Simulation IV (HI-SEAS IV) mission, a 1 year-long isolation study, to investigate microbial transfer between crew and habitat, in order to understand adverse developments which may occur in a future outpost on the Moon or Mars.
Results: Longitudinal 16S rRNA gene profiles, as well as quantitative observations, revealed significant differences in microbial diversity, abundance, and composition between samples of the built environment and its crew. The microbiome composition and diversity associated with abiotic surfaces was found to be rather stable, whereas the microbial skin profiles of individual crew members were highly dynamic, resulting in an increased microbiome diversity at the end of the isolation period. The skin microbiome dynamics were especially pronounced by a regular transfer of the indicator species Methanobrevibacter between crew members within the first 200 days. Quantitative information was used to track the propagation of antimicrobial resistance in the habitat. Together with functional and phenotypic predictions, quantitative and qualitative data supported the observation of a delayed longitudinal microbial homogenization between crew and habitat surfaces which was mainly caused by a malfunctioning sanitary facility.
Conclusions: This study highlights main routes of microbial transfer, interaction of the crew, and origins of microbial dynamics in an isolated environment. We identify key targets of microbial monitoring, and emphasize the need for defined baselines of microbiome diversity and abundance on surfaces and crew skin. Targeted manipulation to counteract adverse developments of the microbiome could be a highly important strategy to ensure safety during future space endeavors
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